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KMID : 1094020140310010066
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Journal of Veterinary Clinics
2014 Volume.31 No. 1 p.66 ~ p.69
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Photodynamic Therapy Using a 632 nm Diode Laser on Otitis Externa of the Dog
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Lee Sug-man
Cho Eun-Sang
Lim Hyun-Soo
Kim Ra-chel
Son Hwa-Young
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Abstract
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Photodynamic therapy (PDT) is an effective method for infectious disease, but as yet, no clinical trial onotitis externa has been conducted in animals. This report describes 4 cases of PDT treatment on severe otitis externain canine. Four canines were treated with various concentrations of 5-aminolevulinic acid hydrochloride (5-ALA) andwith various J (second × power) and irradiated by light-emitting diode light source at 635 nm, respectively. After thePDT applications, canines incubated in the dark for 5 or 6 hr. All patients showed clinical resolution of otitis externaafter PDT treatment at the dose of 0.16~0.3 g ALA and J (54~162 J/cm2). On the basis of these findings, PDT canbe considered to be a new therapeutic approach to severe otitis externa in canine.
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KEYWORD
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photodynamic theraphy, otitis externa, canine, 5-aminolevulinic acid hydrochloride
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